Treatment of obstructive sleep apnea in high risk pregnancy: a multicenter randomized controlled trial.

ABSTRACT:

Background

Obstructive sleep apnea (OSA) during pregnancy is a risk factor for preeclampsia possibly through a link to placental physiology. This study evaluates the efficacy of continuous positive airway pressure (CPAP) on the modulation of blood pressure and the reduction in preeclampsia in women with high-risk pregnancy and OSA.

Methods

A multicenter open-label, randomized controlled trial comparing CPAP treatment versus usual antenatal care was conducted in three academic hospitals in Bangkok, Thailand. Participants included singleton pregnant women aged older than 18 years with any high-risk condition (i.e., chronic hypertension, obesity, history of preeclampsia or gestational diabetes in the previous pregnancy, or diabetes), and OSA (respiratory disturbance index 5-29.

SUBMITTER: Tantrakul V 

PROVIDER: S-EPMC10294320 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature