Repertoire and abundance of secreted virulence factors shape the pathogenic capacity of <i>Pseudomonas syringae</i> pv. aptata.

ABSTRACT: Pseudomonas syringae pv. aptata is a member of the sugar beet pathobiome and the causative agent of leaf spot disease. Like many pathogenic bacteria, P. syringae relies on the secretion of toxins, which manipulate host-pathogen interactions, to establish and maintain an infection. This study analyzes the secretome of six pathogenic P. syringae pv. aptata strains with different defined virulence capacities in order to identify common and strain-specific features, and correlate the secretome with disease outcome. All strains show a high type III secretion system (T3SS) and type VI secretion system (T6SS) activity under apoplast-like conditions mimicking the infection. Surprisingly, we found that low pathogenic strains show a higher secretion of most T3SS substrates, wher

SUBMITTER: Nikolic I 

PROVIDER: S-EPMC10294431 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature