Fibrin degradation products and survival in patients with chronic obstructive pulmonary disease: a protocolized prospective observational study.

ABSTRACT:

Background

Patients with chronic obstructive pulmonary disease (COPD) have a high incidence of cardiovascular disease including thromboembolisms. Fibrin degradation products, like D-dimer, have been associated with death from all causes in healthy individuals and COPD patients. We aimed to determine the (i) association between D-dimer levels and all-cause mortality and time being alive and out of a hospital, (ii) possible modifying effect of anticoagulant treatment,, and (iii) distribution of D-dimer in patients with moderate to severe COPD.

Methods

Results of routinely measured stable phase D-dimer samples from COPD-outpatients at Copenhagen University Hospital - Herlev and Gentofte, COPD-outpatient clinic were collected using the Danish registries. These were used to exami

SUBMITTER: Kamstrup P 

PROVIDER: S-EPMC10294503 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature