Correlation analysis between ¹⁸F-fluorodeoxyglucose positron emission tomography and cognitive function in first diagnosed Parkinson's disease patients.

ABSTRACT:

Objective

Evaluation of the correlation between ¹⁸F-fluorodeoxyglucose-positron emission tomography (¹⁸F-FDG PET) and cognitive function in first-diagnosed and untreated Parkinson's disease (PD) patients.

Materials and method

This cross-sectional study included 84 first diagnosed and untreated PD patients. The individuals were diagnosed by movement disorder experts based on the 2015 MDS Parkinson's disease diagnostic criteria. The patients also underwent ¹⁸F-FDG PET scans and clinical feature assessments including the Montreal Cognitive Assessment (MoCA) scale. Glucose metabolism rates were measured in 26 brain regions using region of interest (ROI) and pixel-wise analyses with displayed Z scores. The cognitive function was assessed by

SUBMITTER: Zhihui S 

PROVIDER: S-EPMC10294683 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature