Biocompatible MgFeCO₃ Layered Double Hydroxide (LDH) for Bone Regeneration-Low-Temperature Processing through Cold Sintering and Freeze-Casting.

ABSTRACT: Layered Double Hydroxides (LDHs) are inorganic compounds of relevance to various domains, where their surface reactivity and/or intercalation capacities can be advantageously exploited for the retention/release of ionic and molecular species. In this study, we have explored specifically the applicability in the field of bone regeneration of one LDH composition, denoted "MgFeCO₃", of which components are already present in vivo, so as to convey a biocompatibility character. The propensity to be used as a bone substitute depends, however, on their ability to allow the fabrication of 3D constructs able to be implanted in bone sites. In this work, we display two appealing approaches for the processing of MgFeCO₃ LDH particles to prepare (i) porous 3D scaffolds by f

SUBMITTER: Kim HJ 

PROVIDER: S-EPMC10294808 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature