Alleviative Effect of Probiotic Ferment on Lawsonia intracellularis Infection in Piglets.

ABSTRACT: (1) Background: Lawsonia intracellularis (LI) is an obligate intracellular Gram-negative bacterium that causes porcine ileitis. Pigs infected with LI have severe ileal lesions and show symptoms of diarrhea, indigestion, and growth retardation. Previous studies found that probiotic ferment (FAM) improved the growth performance, gut barrier, and function in piglets. Therefore, we aimed to reveal the mechanism that FAM alleviates negative performance in LI-challenged piglets by characterizing the changes in intestinal integrity, function, and gut microbiota following FAM supplementation. (2) Methods: Twenty-four healthy piglets were randomly allotted to four treatments. Three groups were challenged with LI; both FAM addition and vaccination were performed to

SUBMITTER: Xu T 

PROVIDER: S-EPMC10295195 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature