Prediction Model for Pre-Eclampsia Using Gestational-Age-Specific Serum Creatinine Distribution.

ABSTRACT: Pre-eclampsia (PE) is a pregnancy-related disease, causing significant threats to both mothers and babies. Numerous studies have identified the association between PE and renal dysfunction. However, in clinical practice, kidney problems in pregnant women are often overlooked due to physiologic adaptations during pregnancy, including renal hyperfiltration. Recent studies have reported serum creatinine (SCr) level distribution based on gestational age (GA) and demonstrated that deviations from the expected patterns can predict adverse pregnancy outcomes, including PE. This study aimed to establish a PE prediction model using expert knowledge and by considering renal physiologic adaptation during pregnancy. This retrospective study included pregnant women who delivered at the Wonju Severance

SUBMITTER: Kang J 

PROVIDER: S-EPMC10295363 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature