Pathogenesis, Intervention, and Current Status of Drug Development for Sarcopenia: A Review.

ABSTRACT: Sarcopenia refers to the loss of muscle strength and mass in older individuals and is a major determinant of fall risk and impaired ability to perform activities of daily living, often leading to disability, loss of independence, and death. Owing to its impact on morbidity, mortality, and healthcare expenditure, sarcopenia in the elderly has become a major focus of research and public policy debates worldwide. Despite its clinical importance, sarcopenia remains under-recognized and poorly managed in routine clinical practice, partly owing to the lack of available diagnostic testing and uniform diagnostic criteria. Since the World Health Organization and the United States assigned a disease code for sarcopenia in 2016, countries worldwide have assigned their own disease codes for sarcopenia

SUBMITTER: Jang JY 

PROVIDER: S-EPMC10295434 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature