Biomarkers of Oxidative Stress in Healthy Infants within the First Three Days after Birth.

ABSTRACT: The clinical relevance of stress biomarkers in newborns is well established. Currently, oxidative stress (OS) parameters are seen to play an important role in neonatal resuscitation guidelines, and a link has been observed between the amount of oxygen delivered and the level of OS and the development of various pathologies. The aim of the current study was to investigate changes in neonatal plasma and urine OS status during the first hours after birth. A lower antioxidant capacity (TAC) and higher levels of malondialdehyde in blood were observed in newborns at the time of birth compared with results 48 h postnatally. The urine revealed a significant and progressive increase in TAC and creatinine during the first 36 h of life, with a progressive decline thereafter. Meanwhile, malondialdehyd

SUBMITTER: Cavia-Saiz M 

PROVIDER: S-EPMC10295668 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature