Low Overpotential Amperometric Sensor Using Yb₂O₃.CuO@rGO Nanocomposite for Sensitive Detection of Ascorbic Acid in Real Samples.

ABSTRACT: The ultimate objective of this research work is to design a sensitive and selective electrochemical sensor for the efficient detection of ascorbic acid (AA), a vital antioxidant found in blood serum that may serve as a biomarker for oxidative stress. To achieve this, we utilized a novel Yb₂O₃.CuO@rGO nanocomposite (NC) as the active material to modify the glassy carbon working electrode (GCE). The structural properties and morphological characteristics of the Yb₂O₃.CuO@rGO NC were investigated using various techniques to ensure their suitability for the sensor. The resulting sensor electrode was able to detect a broad range of AA concentrations (0.5-1571 µM) in neutral phosphate buffer solution, with a high sensitivity of 0.4341 µAµM^-1

SUBMITTER: Ahmed J 

PROVIDER: S-EPMC10295996 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature