Miniaturized Rapid Electrochemical Immunosensor Based on Screen Printed Carbon Electrodes for <i>Mycobacterium tuberculosis</i> Detection.

ABSTRACT: In 2019, over 21% of an estimated 10 million new tuberculosis (TB) patients were either not diagnosed at all or diagnosed without being reported to public health authorities. It is therefore critical to develop newer and more rapid and effective point-of-care diagnostic tools to combat the global TB epidemic. PCR-based diagnostic methods such as Xpert MTB/RIF are quicker than conventional techniques, but their applicability is restricted by the need for specialized laboratory equipment and the substantial cost of scaling-up in low- and middle-income countries where the burden of TB is high. Meanwhile, loop-mediated isothermal amplification (LAMP) amplifies nucleic acids under isothermal conditions with a high efficiency, helps in the early detection and identification of infectious disease

SUBMITTER: Zouaghi N 

PROVIDER: S-EPMC10296126 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature