Clinical Features and Management of Acute and Chronic Radiation-Induced Colitis and Proctopathy.

ABSTRACT:

Background

RICAP is a recognized adverse effect of radiation therapy (RT) that can adversely affect cancer patients' quality of life. Data on the clinical characteristics and outcomes of RICAP are scarce. We aimed to analyze the clinical and endoscopic characteristics of acute or chronic radiation-induced colitis and proctopathy (ARICAP and CRICAP) based on symptom onset after RT (≤ or >45 days, respectively).

Methods

This is a retrospective observational study of a single tertiary cancer center, from January 2010 and December 2018, of cancer patients with endoscopically confirmed ARICAP and CRICAP. We conducted univariate and multivariate logistic regression analyses to associate clinical variables with endoscopic and medical outcomes.

Results

One hundred and twelve

SUBMITTER: Abu-Sbeih H 

PROVIDER: S-EPMC10296205 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature