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Advances in Genetics and Epigenetics of Developmental Coordination Disorder in Children.


ABSTRACT: Developmental coordination disorder (DCD) is a developmental disorder characterized by impaired motor coordination, often co-occurring with attention deficit disorder, autism spectrum disorders, and other psychological and behavioural conditions. The aetiology of DCD is believed to involve brain changes and environmental factors, with genetics also playing a role in its pathogenesis. Recent research has identified several candidate genes and genetic factors associated with motor impairment, including deletions, copy number variations, single nucleotide polymorphisms, and epigenetic modifications. This review provides an overview of the current knowledge in genetic research on DCD, highlighting the importance of continued research into the underlying genetic mechanisms. While evidence sugge

SUBMITTER: You H 

PROVIDER: S-EPMC10296699 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature