Understanding target-specific effects of antidepressant drug pollution on molluscs: A systematic review protocol.

ABSTRACT:

Background

The environmental prevalence of widely prescribed human pharmaceuticals that target key evolutionary conserved biomolecules present across phyla is concerning. Antidepressants, one of the most widely consumed pharmaceuticals globally, have been developed to target biomolecules modulating monoaminergic neurotransmission, thus interfering with the endogenous regulation of multiple key neurophysiological processes. Furthermore, rising prescription and consumption rates of antidepressants caused by the burgeoning incidence of depression is consistent with increasing reports of antidepressant detection in aquatic environments worldwide. Consequently, there are growing concerns that long-term exposure to environmental levels of antidepressants may cause adverse drug target-spe

SUBMITTER: Imiuwa ME 

PROVIDER: S-EPMC10298782 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature