Intraoperative Visualization and Treatment of Salivary Gland Dysfunction in Sjogren's Syndrome Patients Using Contrast-Enhanced Ultrasound Sialendoscopy (CEUSS).

ABSTRACT: In sialendoscopy, ducts are dilated and the salivary glands are irrigated with saline. Contrast-enhanced ultrasound sialendoscopy (CEUSS), using microbubbles, may facilitate the monitoring of irrigation solution penetration in the ductal system and parenchyma. It is imperative to test CEUSS for its safety and feasibility in Sjögren's syndrome (SS) patients. CEUSS was performed on 10 SS patients. The primary outcomes were safety, determined by the occurrence of (serious) adverse events ((S)AEs), and feasibility. The secondary outcomes were unstimulated and stimulated whole saliva (UWS and SWS) flow rates, xerostomia inventory (XI), clinical oral dryness score, pain, EULAR Sjögren's syndrome patient reported index (ESSPRI), and gland topographical alterations. CEUSS was technically feasible

SUBMITTER: Karagozoglu KH 

PROVIDER: S-EPMC10298935 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature