Rotational Thromboelastometry (ROTEM^®) in Relation to Inflammatory Biomarkers and Clinical Outcome in COVID-19 Patients.

ABSTRACT: Background: The pathogenesis of hypercoagulability in COVID-19 patients is complex and not fully understood. Rotational thromboelastometry (ROTEM^®) is a viscoelastic method that allows the definition of a patient's hemostatic profile. This study aimed to assess the relationship between ROTEM^® parameters, the profile of inflammatory cytokines, and clinical outcomes in COVID-19 patients. Methods: A total of 63 participants (n = 29 symptomatic non-ICU COVID-19 patients, and n = 34 healthy controls) were prospectively included in the study. We assessed the relationship between the parameters of three ROTEM^® tests (NATEM^®, EXTEM^®, and FIBTEM^®) and levels of CRP, interleukin-8, interleukin-1β, interleuk

SUBMITTER: Rogalski P 

PROVIDER: S-EPMC10299160 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature