The Efficacy of Probiotics, Prebiotics, and Synbiotics in Patients Who Have Undergone Abdominal Operation, in Terms of Bowel Function Post-Operatively: A Network Meta-Analysis.

ABSTRACT:

Background

Abdominal operations may lead to post-operative bowel dysfunction, while administration of probiotics, prebiotics and synbiotics may limit its manifestation. Τhe study aimed to assess the efficacy of probiotics, prebiotics and synbiotics in patients who undergone abdominal operation, in terms of bowel function post-operatively.

Methods

PubMed, Scopus, Cochrane Central Register of Controlled Trials (Central), Embase, US Registry of clinical trials, and sources of grey literature were searched. The relative effect sizes were estimated, and we obtained the relative ranking of the interventions using cumulative ranking curves.

Results

In total, 30 studies were included in the analysis. For the outcome of post-operative ileus, probiotics was superior to placebo/

SUBMITTER: Ioannidis O 

PROVIDER: S-EPMC10299319 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature