Electrochemical sensor based on the synergy between Cucurbit[8]uril and 2D-MoS₂ for enhanced melatonin quantification.

ABSTRACT: We present the development of an electrochemical sensor towards melatonin determination based on the synergistic effect between MoS₂ nanosheets and cucurbit[8]uril. For the sensor construction cucurbit[8]uril suspensions were prepared in water, and MoS₂ nanosheets were obtained by liquid exfoliation in ethanol:water. The sensing platform was topographically characterized by Atomic Force Microscopy. Electrochemical Impedance Spectroscopy experiments allowed us to study the charge transfer process during melatonin oxidation. Moreover, stoichiometry of the resulting complex has also been determined. After the optimization of the sensor construction and the experimental variables involved in the Differential Pulse Voltammetric response of melatonin, detection limit of 3.8

SUBMITTER: Martinez-Moro R 

PROVIDER: S-EPMC10300025 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature