Multiple factors contribute to flight behaviors during fear conditioning.

ABSTRACT: Shifting defensive mode from one to another by the imminence of threat is crucial for survival. The transition of defensive mode from freezing to flight is observed during the modified fear conditioning, however, the flight during fear conditioning is not well characterized. To characterize the flight behaviors during the fear conditioning, we conducted experiments in male mice focusing on the influence of the context, the intensity of the unconditioned stimulus and conditioned stimulus (CS), the schedule of conditioning, and the state of the subject. Flight behaviors triggered by salient CS showed characteristics of fear-potentiated defensive behaviors depending on the conditioned context, while repetitive conditioning enhanced the expression of the flight and developed an association bet

SUBMITTER: Furuyama T 

PROVIDER: S-EPMC10300071 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature