Short-term homeostatic visual neuroplasticity in adolescents after two hours of monocular deprivation.

ABSTRACT: In healthy adults with normal vision, temporary deprivation of one eye's visual experience produces transient yet robust homeostatic plasticity effects, where the deprived eye becomes more dominant. This shift in ocular dominance is short-lived and compensatory. Previous work shows that monocular deprivation decreases resting state gamma aminobutyric acid (GABA; inhibitory neurotransmitter) levels in visual cortex, and that those with the greatest reduction in GABA have stronger shifts due to monocular deprivation. Components of the GABAergic system in visual cortex vary with age (early childhood, early teen years, ageing); hence if GABA is critical to homeostatic plasticity within the visual system, adolescence may be a key developmental period where differences in plasticity manifest. He

SUBMITTER: Nguyen BN 

PROVIDER: S-EPMC10300437 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature