Injectable antibacterial Ag-HA/ GelMA hydrogel for bone tissue engineering.

ABSTRACT: Background: Fracture or bone defect caused by accidental trauma or disease is a growing medical problem that threats to human health.Currently, most orthopedic implant materials must be removed via follow-up surgery, which requires a lengthy recovery period and may result in bacterial infection. Building bone tissue engineering scaffolds with hydrogel as a an efficient therapeutic strategy has outstanding bionic efficiency.By combining some bionic inorganic particles and hydrogels to imitate the organic-inorganic characteristics of natural bone extracellular matrix, developing injectable multifunctional hydrogels with bone tissue repair effects and also displaying excellent antibacterial activity possesses attractive advantages in the field of minimally invasive therapy in clinical.

SUBMITTER: Wang J 

PROVIDER: S-EPMC10300446 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature