Firefighting and Cancer: A Meta-analysis of Cohort Studies in the Context of Cancer Hazard Identification.

ABSTRACT:

Objective

We performed a meta-analysis of epidemiological results for the association between occupational exposure as a firefighter and cancer as part of the broader evidence synthesis work of the IARCMonographs program.

Methods

A systematic literature search was conducted to identify cohort studies of firefighters followed for cancer incidence and mortality. Studies were evaluated for the influence of key biases on results. Random-effects meta-analysis models were used to estimate the association between ever-employment and duration of employment as a firefighter and risk of 12 selected cancers. The impact of bias was explored in sensitivity analyses.

Results

Among the 16 included cancer incidence studies, the estimated meta-rate ratio, 95% confidence

SUBMITTER: DeBono NL 

PROVIDER: S-EPMC10300491 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature