The impact of temporal lobe epilepsy surgery on picture naming and its relationship to network metric change.

ABSTRACT:

Background

Anterior temporal lobe resection (ATLR) is a successful treatment for medically-refractory temporal lobe epilepsy (TLE). In the language-dominant hemisphere, 30%- 50% of individuals experience a naming decline which can impact upon daily life. Measures of structural networks are associated with language performance pre-operatively. It is unclear if analysis of network measures may predict post-operative decline.

Methods

White matter fibre tractography was performed on preoperative diffusion MRI of 44 left lateralised and left resection individuals with TLE to reconstruct the preoperative structural network. Resection masks, drawn on co-registered pre- and post-operative T1-weighted MRI scans, were used as exclusion regions on pre-operative tractography to estimate

SUBMITTER: Peter Binding L 

PROVIDER: S-EPMC10300575 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature