Value-based decision-making network functional connectivity correlates with substance use and delay discounting behaviour among young adults.

ABSTRACT: Substance use disorders are characterized by reduced control over the quantity and frequency of psychoactive substance use and impairments in social and occupational functioning. They are associated with poor treatment compliance and high rates of relapse. Identification of neural susceptibility biomarkers that index risk for developing a substance use disorder can facilitate earlier identification and treatment. Here, we aimed to identify the neurobiological correlates of substance use frequency and severity amongst a sample of 1,200 (652 females) participants aged 22-37 years from the Human Connectome Project. Substance use behaviour across eight classes (alcohol, tobacco, marijuana, sedatives, hallucinogens, cocaine, stimulants, opiates) was measured using the Semi-Structured Assessment

SUBMITTER: Loganathan K 

PROVIDER: S-EPMC10300614 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature