Development of a predictive risk stratification tool to identify the population over age 45 at risk for new-onset stroke within 7 years.

ABSTRACT:

Background and purpose

With the acceleration of the aging process of society, stroke has become a major health problem in the middle-aged and elderly population. A number of new stroke risk factors have been recently found. It is necessary to develop a predictive risk stratification tool using multidimensional risk factors to identify people at high risk for stroke.

Methods

The study included 5,844 people (age ≥ 45 years) who participated in the China Health and Retirement Longitudinal Study in 2011 and its follow-up up to 2018. The population samples were divided into training set and validation set according to 1:1. A LASSO Cox screening was performed to identify the predictors of new-onset stroke. A nomogram was developed, and the population was stratified according to th

SUBMITTER: Yang K 

PROVIDER: S-EPMC10301757 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature