Mexican Native Black Bean Anthocyanin-Rich Extracts Modulate Biological Markers Associated with Inflammation.

ABSTRACT: This work aimed to obtain and characterize anthocyanin-rich extracts (ARE) from native black beans and evaluate their antioxidant and anti-inflammatory potential. The initial extract was obtained by supercritical fluids (RE) and purified using Amberlite^® XAD-7 resin (PE). RE and PE were fractionated using countercurrent chromatography, and four fractions were obtained (REF1 and REF2 from RE, PEF1, and PEF2 from PE). ARE and fractions were characterized, and the biological potential was evaluated. ABTS IC₅₀ values ranged from 7.9 to 139.2 (mg C3GE/L), DPPH IC₅₀ ranged from 9.2 to 117.2 (mg C3GE/L), and NO IC₅₀ ranged from 0.6 to143.8 (mg C3GE/L) (p < 0.05). COX-1 IC₅₀ ranged from 0.1 to 0.9 (mg C3GE/L), COX-2 IC₅₀ rang

SUBMITTER: Contreras J 

PROVIDER: S-EPMC10301825 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature