Clonal dissemination of highly virulent Serratia marcescens strains producing KPC-2 in food-producing animals.

ABSTRACT: Serratia marcescens is a Gram-negative bacterium presenting intrinsic resistance to polymyxins that has emerged as an important human pathogen. Although previous studies reported the occurrence of multidrug-resistance (MDR) S. marcescens isolates in the nosocomial settings, herein, we described isolates of this extensively drug-resistant (XDR) species recovered from stool samples of food-producing animals in the Brazilian Amazon region. Three carbapenem-resistant S. marcescens strains were recovered from stool samples of poultry and cattle. Genetic similarity analysis showed that these strains belonged to the same clone. Whole-genome sequencing of a representative strain (SMA412) revealed a resistome composed of genes encoding resistance to β-lactams [bla_KP

SUBMITTER: Valiatti TB 

PROVIDER: S-EPMC10302155 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature