ABUNDANCE AND MULTIMODAL VISIBILITY OF SOFT DRUSEN IN EARLY AGE-RELATED MACULAR DEGENERATION: A Clinicopathologic Correlation.

ABSTRACT:

Purpose

To determine the abundance and multimodal visibility of drusen and basal linear deposit (BLinD) in early age-related macular degeneration.

Methods

A 69-year-old white man was imaged by color fundus photography and red free photography, fundus autofluorescence, and optical coherence tomography. From en face images, we determined the drusen field, drusen area, and equivalent diameters of individual drusen. From high-resolution light-microscopic histology (6 months after the last clinic visit), we determined the area of drusen, BLinD, and pre-BLinD in a subretinal pigment epithelium-basal lamina lipid field.

Results

In right and left eyes, respectively, BLinD covered 40% and 46% of the lipid field, versus 21% and 14% covered by drusen. The lipid field was covered

SUBMITTER: Chen L 

PROVIDER: S-EPMC10302298 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature