Orodispersible Film Based on Maltodextrin: A Convenient and Suitable Method for Iron Supplementation.

ABSTRACT: Orodispersible film (ODF) is an innovative dosage form used to administer drugs and nutrients, designed to disintegrate or dissolve in the oral cavity without needing water. One of the advantages of ODF is that it is suitable for administration in older people and children who have difficulty swallowing because of psychological or physiological deficiencies. This article describes the development of an ODF based on maltodextrin, which is easy to administer, has a pleasant taste, and is suitable for iron supplementation. An ODF containing 30 mg of iron as pyrophosphate and 400 µg of folic acid (iron ODF) was developed and manufactured on an industrial scale. The kinetic profile for serum iron and folic acid upon consumption of ODF compared with a Sucrosomial^® iron capsule (known

SUBMITTER: Cupone IE 

PROVIDER: S-EPMC10303362 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature