Lipoprotein Lipase Activity Does Not Differ in the Serum Environment of Vegans and Omnivores.

ABSTRACT: Although vegan diets have been reported to be associated with a reduced risk of cardiovascular disease, it was not known whether this might be partly due to vegan diets' effects on plasma triglyceride metabolism. This study aimed to investigate if there are differences in the activity of lipoprotein lipase (LPL), an enzyme that functions at the vascular endothelium and is responsible for triglyceride breakdown, in sera obtained from vegans and omnivores. LPL activity was assessed using isothermal titration calorimetry, which allows measurements in undiluted serum samples, mimicking physiological conditions. Fasted sera from 31 healthy participants (12F 2M vegans, 11F 6M omnivores) were analyzed. The results indicated no significant differences in average LPL activity between the vegan and

SUBMITTER: Seeba NN 

PROVIDER: S-EPMC10303673 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature