Photoelectrochemical biosensor based on SiW₁₂@CdS quantum dots for the highly sensitive detection of HPV 16 DNA.

ABSTRACT: A highly sensitive biosensor for detecting HPV 16 DNA was prepared based on Keggin-type polyoxometalate (SiW₁₂)-grafted CdS quantum dots (SiW₁₂@CdS QDs) and colloidal gold nanoparticles (Au NPs), which exhibited remarkable selectivity and sensitivity upon target DNA detection because of its excellent photoelectrochemical (PEC) response. Here, an enhanced photoelectronic response ability was achieved with the strong association of SiW₁₂@CdS QDs by polyoxometalate modification, which was developed through a convenient hydrothermal process. Furthermore, on Au NP-modified indium tin oxide slides, a multiple-site tripodal DNA walker sensing platform coupled with T7 exonuclease was successfully fabricated with SiW₁₂@CdS QDs/NP DNA as a probe for detect

SUBMITTER: Cheng Y 

PROVIDER: S-EPMC10303914 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature