Characterization of Collagen Binding Activity of Clostridium perfringens Strains Isolated from Broiler Chickens.

ABSTRACT: Clostridium perfringens is the etiological agent for necrotic enteritis (NE) in broiler chickens, which causes a substantial economic loss of an estimated USD 6 billion annually in the global poultry industry. Collagen adhesion is involved in the NE pathogenesis in poultry. In this study, the binding capabilities of chicken C. perfringens isolates of various genetic backgrounds (netB^-tpeL^-, netB⁺tpeL^-, netB⁺tpeL⁺) to collagen types I-V and gelatin were examined, and the putative adhesin protein cnaA gene was investigated at the genomic level. In total, 28 C. perfringens strains from healthy and NE-inflicted sick chickens were examined. The results on collagen adhesin-encoding

SUBMITTER: Sun Z 

PROVIDER: S-EPMC10303977 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature