Incidence and risk factors of tuberculosis in systemic lupus erythematosus patients: a multi-center prospective cohort study.

ABSTRACT:

Objectives

Both burdens of tuberculosis (TB) and systemic lupus erythematosus (SLE) in China are ranked as top three in the world. SLE patients are at high risk for TB, but so far, there are no guidelines for TB prevention and management targeting this population in China. This study aims to investigate the incidence of active tuberculosis (ATB) and to explore the risk factors for developing ATB in SLE patients, and to provide evidence for TB prevention and management for SLE patients in China.

Methods

A multi-center prospective cohort study was conducted. SLE patients were enrolled from clinics and wards of 13 tertiary hospitals in Eastern, Middle, and Western China from September 2014 to March 2016. Baseline demographic features, TB infection status, clinical information,

SUBMITTER: Zhang L 

PROVIDER: S-EPMC10304284 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature