Mammographic density in relation to breast cancer recurrence and survival in women receiving neoadjuvant chemotherapy.

ABSTRACT:

Objective

The association between mammographic density (MD) and breast cancer (BC) recurrence and survival remains unclear. Patients receiving neoadjuvant chemotherapy (NACT) are in a vulnerable situation with the tumor within the breast during treatment. This study evaluated the association between MD and recurrence/survival in BC patients treated with NACT.

Methods

Patients with BC treated with NACT in Sweden (2005-2016) were retrospectively included (N=302). Associations between MD (Breast Imaging-Reporting and Data System (BI-RADS) 5^th Edition) and recurrence-free/BC-specific survival at follow-up (Q1 2022) were addressed. Hazard ratios (HRs) for recurrence/BC-specific survival (BI-RADS a/b/c vs. d) were estimated using Cox regression analysis and adjusted for

SUBMITTER: Zdanowski A 

PROVIDER: S-EPMC10304818 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature