Ontology highlight
ABSTRACT:
SUBMITTER: Lara-Espinosa JV
PROVIDER: S-EPMC10305529 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Lara-Espinosa Jacqueline V JV Arce-Aceves María Fernanda MF Barrios-Payán Jorge J Mata-Espinosa Dulce D Lozano-Ordaz Vasti V Becerril-Villanueva Enrique E Ponce-Regalado María Dolores MD Hernández-Pando Rogelio R
Microorganisms 20230610 6
Tuberculosis (TB) is the deadliest disease caused by a bacterial agent. Glucocorticoids (GCs) have a typical anti-inflammatory effect, but recently it has been shown that they can present proinflammatory activity, mainly by increasing molecules from innate immunity. In the current study, we evaluated the effect of low doses of dexamethasone on <i>Mycobacterium tuberculosis</i> in vivo and in vitro. We used an established mice model of progressing tuberculosis (TB) in the in vivo studies. Intratr ...[more]