Ontology highlight
ABSTRACT:
SUBMITTER: Nakahara H
PROVIDER: S-EPMC10306108 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Chemical science 20230501 25
In the last couple of decades, technologies and strategies for peptide synthesis have advanced rapidly. Although solid-phase peptide synthesis (SPPS) and liquid-phase peptide synthesis (LPPS) have contributed significantly to the development of the field, there have been remaining challenges for C-terminal modifications of peptide compounds in SPPS and LPPS. Orthogonal to the current standard approach that relies on installation of a carrier molecule at the C-terminus of amino acids, we develope ...[more]