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Treatment of Iron Deficiency in Heart Failure.


ABSTRACT:

Purpose of review

Heart failure (HF) is commonly associated with iron deficiency (ID), defined as insufficient levels of iron to meet physiological demands. ID's association with anaemia is well understood but it is increasingly recognised as an important comorbidity in HF, even in the absence of anaemia. This review summarises contemporary evidence for the measurement and treatment of ID, in both HFrEF and HFpEF, and specific HF aetiologies, and highlights important gaps in the evidence-base.

Recent findings

ID is common among patients with HF and associated with increased morbidity and mortality. Correcting ID in patients with HF can impact upon functional status, exercise tolerance, symptoms, and overall quality of life, irrespective of anaemia status. ID is a modifiable

SUBMITTER: Shamsi A 

PROVIDER: S-EPMC10307722 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature