Durability of immune response after SARS-CoV-2 vaccination in patients with chronic liver disease.

ABSTRACT:

Aim

The present study aimed to evaluate the durability of immune response after basic and booster immunization with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in patients with chronic liver disease (CLD).

Methods

Patients with CLD and complete basic or booster immunization with SARS-CoV-2 vaccines were included in this study. Based on the vaccination situation, they were divided into the basic immunity group (Basic) and the booster immunity group (Booster), which were then subdivided into four groups according to the time interval from completion of basic immunization or booster immunization to serological specimen collection. The positive rates and antibody titers of novel coronavirus neutralizing antibody (nCoV NTAb) and novel coronavirus spike r

SUBMITTER: Song R 

PROVIDER: S-EPMC10308026 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature