Human blood plasma biomarkers of diet and weight loss among centrally obese subjects in a New Nordic Diet intervention.

ABSTRACT:

Scope

The New Nordic Diet (NND) has been shown to promote weight loss and lower blood pressure amongst obese people. This study investigates blood plasma metabolite and lipoprotein biomarkers differentiating subjects who followed Average Danish Diet (ADD) or NND. The study also evaluates how the individual response to the diet is reflected in the metabolic differences between NND subjects who lost or maintained their pre-intervention weight.

Methods

Centrally obese Danes (BMI >25) followed NND (90 subjects) or ADD (56 subjects) for 6 months. Fasting blood plasma samples, collected at three time-points during the intervention, were screened for metabolites and lipoproteins (LPs) using proton nuclear magnetic resonance spectroscopy. In total, 154 metabolites and 65 lipoprotein

SUBMITTER: Trimigno A 

PROVIDER: S-EPMC10308042 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature