10 Years of SYNTAX: Closing an Era of Clinical Research After Identifying New Outcome Determinants.

ABSTRACT: The SYNTAX trial randomized patients equally eligible for coronary artery bypass grafting or percutaneous coronary intervention using the Heart Team approach. The SYNTAXES study achieved a follow-up rate of 93.8% and reported the 10-year vital status. Factors associated with increased mortality at 10 years were pharmacologically treated diabetes mellitus, increased waist circumference, reduced left ventricular function, prior cerebrovascular and peripheral vascular disease, western Europe and North American descent, current smoking, chronic obstructive pulmonary disease, elevated C-reactive protein, anemia, and an increase in HbA1c. Procedural factors associated with higher 10 years mortality include periprocedural myocardial infarction, extensive stenting, small stents, ≥1 heavily calcifi

SUBMITTER: Serruys PW 

PROVIDER: S-EPMC10308124 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature