Circumferential Pulmonary Vein Isolation With vs Without Additional Low-Voltage-Area Ablation in Older Patients With Paroxysmal Atrial Fibrillation: A Randomized Clinical Trial.

ABSTRACT:

Importance

The overall success rate of circumferential pulmonary vein isolation (CPVI) treatment in patients with paroxysmal atrial fibrillation (AF) remains suboptimal, especially in older patients.

Objective

To explore the incremental benefit of low-voltage-area ablation after CPVI in older patients with paroxysmal AF.

Design, setting, and participants

This randomized clinical trial was an investigator-initiated trial to compare the efficacy of additional low-voltage-area ablation beyond CPVI vs CPVI alone in older patients with paroxysmal AF. Participants were patients aged 65 to 80 years with paroxysmal AF who were referred for catheter ablation. They were enrolled in 14 tertiary hospitals in China from April 1, 2018, to August 3, 2020, and follow-up occurred thro

SUBMITTER: Chen H 

PROVIDER: S-EPMC10308299 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature