Reproduction and genetic causal attribution of epilepsy.

ABSTRACT:

Objective

This study addresses the contribution of genetics-related concerns to reduced childbearing among people with epilepsy.

Methods

Surveys were completed by 606 adult patients with epilepsy of unknown cause at our medical center. Poisson regression analysis was used to assess the relations of number of offspring to: (1) genetic attribution (GA: participants' belief that genetics was a cause of their epilepsy), assessed via a novel scale developed from four survey items (Cronbach's alpha = .89), (2) participants' estimates of epilepsy risk in the child of a parent with epilepsy (1%, 5%-10%, 25%, and 50%-100%), and (3) participants' reports of the influence on their reproductive decisions of "the chance of having a child with epilepsy" (none/weak/moderate, strong/very st

SUBMITTER: Ottman R 

PROVIDER: S-EPMC10308304 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature