Effect measure modification of the association between short-term exposures to PM_2.5 and hospitalizations by longs-term PM_2.5 exposure among a cohort of people with Chronic Obstructive Pulmonary Disease (COPD) in North Carolina, 2002-2015.

ABSTRACT:

Background

Approximately nine million adults in the United States are living with chronic obstructive pulmonary disease (COPD), and positive associations between short-term air pollution exposure and increased risk of COPD hospitalizations in older adults are consistently reported. We examined the association between short-term PM_2.5 exposure and hospitalizations and assessed if there is modification by long-term exposure in a cohort of individuals with COPD.

Methods

In a time-referent case-crossover design, we used a cohort of randomly selected individuals with electronic health records from the University of North Carolina Healthcare System, restricted to patients with a medical encounter coded with a COPD diagnosis from 2004-2016 (n = 520), and estimated ambien

SUBMITTER: Cowan KN 

PROVIDER: S-EPMC10308617 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature