The prevalence and risk factors for cognitive impairment in obesity and NAFLD.

ABSTRACT:

Background

Severe obesity may be accompanied by cognitive dysfunction and NAFLD, but the associations remain unclear. We describe the prevalence and features of cognitive dysfunction and examine the associations between cognitive dysfunction and the presence and severity of NAFLD, and the associations between cognitive dysfunction and signs of other obesity-related comorbidities and neuronal damage.

Methods

A cross-sectional study of patients with a body mass index of 35 kg/m2 underwent evaluation for bariatric surgery. They were screened for adiposity-related comorbidity and underwent a liver biopsy and basic cognitive testing with the Continuous Reaction Time test, the Portosystemic Encephalopathy Syndrome test, and the Stroop Test. A representative subgroup also underwent

SUBMITTER: Wernberg CW 

PROVIDER: S-EPMC10309508 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature