Cause-specific mortality among patients with cirrhosis in a population-based cohort study in Ontario (2000-2017).

ABSTRACT:

Background

Although patients with cirrhosis are at increased risk of death, the exact causes of death have not been reported in the contemporary era. This study aimed to describe cause-specific mortality in patients with cirrhosis in the general population.

Methods

Retrospective cohort study using administrative health care data from Ontario, Canada. Adult patients with cirrhosis from 2000-2017 were identified. Cirrhosis etiologies were defined as HCV, HBV, alcohol-associated liver disease (ALD), NAFLD, or autoimmune liver disease/other with validated algorithms. Patients were followed until death, liver transplant, or end of study. Primary outcome was the cause of death as liver-related, cardiovascular disease, non-hepatic malignancy, and external causes (accident/self-harm

SUBMITTER: Wang PL 

PROVIDER: S-EPMC10309525 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature