Impact of cell-free supernatant of lactic acid bacteria on Staphylococcus aureus biofilm and its metabolites.

ABSTRACT:

Introduction

A safe bio-preservative agent, lactic acid bacteria (LAB) can inhibit the growth of pathogenic bacteria and spoilage organisms. Its cell-free supernatant (LAB-CFS), which is rich in bioactive compounds, is what makes LAB antibacterial work.

Methods

This study focused on the changes in biofilm activity and related metabolic pathways of S. aureus treated with lactic acid bacteria planktonic CFS (LAB-pk-CFS) and biofilm state (LAB-bf-CFS).

Results

The findings demonstrated that the LAB-CFS treatment considerably slowed Staphylococcus aureus (S. aureus) growth and prevented it from forming biofilms. Additionally, it inhibits the physiological traits of the S. aureus biofilm, including hydrophobicity, motility, eDNA, and PIA associa

SUBMITTER: Mao Y 

PROVIDER: S-EPMC10310794 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature