Subcutaneous progesterone administration provides a similar ongoing pregnancy rate compared with intramuscular progesterone administration in hormone replacement therapy frozen embryo transfer cycles.

ABSTRACT:

Objective

To compare the ongoing pregnancy rates (OPRs) for subcutaneous progesterone (SC-P) to intramuscular progesterone (IM-P) in hormone replacement therapy used in frozen embryo transfer (FET) cycles.

Design

Prospective nonrandomized cohort study.

Setting

Private fertility clinic.

Patients

The study enrolled 224 patients scheduled for hormone replacement therapy (HRT)-FET cycles with SC-P (n = 133) or IM-P (n = 91). The route of P administration was decided according to the patient's preference and accessibility to the hospital. In the first FET cycle of a freeze-all cycle using single blastocyst transfers, a woman aged ≤35 was included.

Main outcomes

Ongoing pregnancy (OP).

Results

The demographic, cycle, and embryologic characteristics were

SUBMITTER: Boynukalin FK 

PROVIDER: S-EPMC10310939 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature