Priorities in Chronic nonbacterial osteomyelitis (CNO) - results from an international survey and roundtable discussions.

ABSTRACT:

Objective

Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory bone disorder that predominantly affects children and young people. The pathophysiology and molecular mechanisms of CNO remain poorly understood, and diagnostic criteria and biomarkers are lacking. As a result, treatment is empiric and follows personal experience, case series and expert consensus plans.

Methods

A survey was designed to gain insight on clinician and patient experiences of diagnosing and treating CNO and to collate opinions on research priorities. A version containing 24 questions was circulated among international expert clinicians and clinical academics (27 contacted, 21 responses). An equivalent questionnaire containing 20 questions was shared to explore the experience and priorities

SUBMITTER: Mohanna M 

PROVIDER: S-EPMC10311767 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature