Proton beam therapy in multimodal treatment for locally advanced squamous cell carcinoma of the nasal cavity and paranasal sinus.

ABSTRACT:

Background

To evaluate proton beam therapy (PBT) in multimodal treatment for locally advanced squamous cell carcinoma of the nasal cavity and paranasal sinus (NPSCC).

Methods

The cases in this study included T3 and T4 NPSCC without distant metastases that were treated at our center using PBT between July 2003 and December 2020. These cases were classified into 3 groups based on resectability and treatment strategy: surgery followed by postoperative PBT (group A); those indicated to be resectable, but the patient refused surgery and received radical PBT (group B); and those declared unresectable based on the extent of the tumor and treated with radical PBT (group C).

Results

The study included 37 cases, with 10, 9 and 18 in groups A, B and C, respectively. The median f

SUBMITTER: Saito T 

PROVIDER: S-EPMC10311771 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature