SARS-CoV-2 infection and pulmonary tuberculosis in children and adolescents: a case-control study.

ABSTRACT:

Background

The Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) pandemic has had an impact on the global tuberculosis (TB) epidemic but evidence on the possible interaction between SARS-CoV-2 and TB, especially in children and adolescents, remains limited. We aimed to evaluate the relationship between previous infection with SARS-CoV-2 and the risk of TB in children and adolescents.

Methods

An unmatched case-control study was conducted using SARS-CoV-2 unvaccinated children and adolescents recruited into two observational TB studies (Teen TB and Umoya), between November 2020 and November 2021, in Cape Town, South Africa. Sixty-four individuals with pulmonary TB (aged < 20 years) and 99 individuals without pulmonary TB (aged < 20 years) were included. Demographics

SUBMITTER: Swanepoel J 

PROVIDER: S-EPMC10311805 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature